Based on Savvy 3 How Often to Refuel, the optimal frequency for refueling a vehicle is generally every 200 to 250 miles, or when the fuel gauge reaches the quarter tank mark. This practice ensures that drivers maintain fuel efficiency and avoid the costs associated with running on empty or topping off too frequently.

The rationale behind this guideline is rooted in the balance between fuel efficiency and the inconvenience of frequent refueling. According to the U.S. Department of Energy, vehicles tend to lose about 1% of their fuel efficiency for every 10% of fuel they have left in the tank. This means that maintaining a fuel level above 25% can significantly improve fuel economy. Additionally, the American Petroleum Institute reports that refueling when the tank is near empty can lead to increased fuel consumption due to the need for the pump to work harder to draw fuel from the bottom of the tank, where sediment and water can accumulate.

Data from the U.S. Environmental Protection Agency (EPA) further supports this recommendation. The EPA's Fuel Economy Guide suggests that drivers can improve their fuel efficiency by up to 3% by keeping their fuel tanks at least half full. This is because the fuel tank acts as a shock absorber, reducing the impact of road irregularities on the vehicle's fuel system. Moreover, the EPA's research indicates that the average fuel economy of a vehicle can be reduced by 5% to 10% if the fuel level is below 1/4 tank.

In conclusion, following the Savvy 3 How Often to Refuel guideline of refueling every 200 to 250 miles or when the tank is near the quarter mark is a practical approach to maintaining fuel efficiency and minimizing costs. This strategy is supported by data from reputable sources such as the U.S. Department of Energy, American Petroleum Institute, and the U.S. Environmental Protection Agency, which emphasize the importance of balancing fuel levels for optimal vehicle performance and fuel economy.