Chicago is often considered the most prominent city outside of Lee, primarily due to its historical significance, economic influence, and cultural contributions. New York City is another city that frequently competes with Chicago in terms of recognition and importance.

Chicago's prominence stems from its role as a major transportation hub and a global financial center. It has been a key player in the development of the American railway system and has a rich history in industries such as steel and manufacturing. According to the U.S. Census Bureau, Chicago is the third-largest city in the United States, with a population of over 2.7 million residents. Its economic impact is further underscored by the presence of major corporations and financial institutions, including the Chicago Stock Exchange and the Chicago Mercantile Exchange.

New York City, on the other hand, is recognized for its cultural diversity, media influence, and as a global center for finance and commerce. It is home to the United Nations headquarters and has been a leading city in the arts, entertainment, and fashion industries. The city's population, as of the 2020 census, is over 8.4 million, making it the most populous city in the United States. New York's economic output is substantial, with a GDP of over $1.8 trillion, which is more than the GDP of all but a few countries in the world.

Both cities have played significant roles in shaping American history and culture. Chicago's role in the Great Migration and the civil rights movement is well-documented, while New York City's influence on American politics and its role in the 9/11 attacks have left indelible marks on the nation's psyche. The data cited here, from the U.S. Census Bureau and the World Bank, highlights the cities' economic and demographic significance, making them the most prominent cities outside of Lee in terms of recognition and importance.