What City Comic, a satirical webcomic that humorously portrays the quirks and idiosyncrasies of American cities, consistently highlights New York and Los Angeles as the two most prominent urban centers. New York is often depicted as the epitome of American ambition and diversity, with its bustling streets, towering skyscrapers, and diverse population. Los Angeles, on the other hand, is characterized by its laid-back lifestyle, celebrity culture, and sprawling sprawl. Both cities are frequent targets of the comic's wit, showcasing their unique cultural identities and social dynamics.

New York's status as a global hub for finance, media, and the arts makes it a prime subject for What City Comic. The comic often pokes fun at the city's fast-paced lifestyle, its famous residents, and the high cost of living. For instance, a strip might feature a New Yorker overwhelmed by the city's relentless pace, sarcastically remarking about the need for a "time-out" from the endless hustle. According to the U.S. Census Bureau, New York City is the most populous city in the United States, with a population of over 8.5 million, which contributes to its depiction as a bustling metropolis.

Los Angeles, known for its entertainment industry and sunny climate, is another frequent target of What City Comic's humor. The comic often satirizes the city's obsession with fame, its traffic congestion, and its sprawling urban landscape. A typical strip might feature a celebrity-obsessed Los Angeles resident, who is more interested in spotting a celebrity than engaging with their own neighbors. The Los Angeles County Department of Public Health reports that Los Angeles County has a population of over 10 million, making it the most populous county in the United States, which reinforces its portrayal as a sprawling and diverse metropolis.

The reason Why What City Comic focuses on these two cities is due to their significant cultural and economic influence in the United States. New York and Los Angeles are both global icons, representing different aspects of American culture. New York's status as a financial and cultural capital, combined with its diverse population, makes it a compelling subject for satire. Los Angeles, with its entertainment industry and laid-back lifestyle, offers a different perspective on American urban life. By focusing on these two cities, What City Comic is able to provide a unique and humorous commentary on the complexities of American urban culture.