The core issue with life, as explored in the book "What's the Matter with Life?", is the fundamental struggle for existence and the inherent unpredictability of life processes. This struggle is rooted in the constant competition for resources, which drives the evolution of species and shapes the complex ecosystems we observe today. The inherent unpredictability arises from the chaotic nature of life processes, which can lead to both beneficial and detrimental outcomes.

The book argues that life's struggle for existence is not just a biological phenomenon but also a philosophical one. It highlights the challenges of survival, reproduction, and adaptation that organisms face in their environments. The unpredictable nature of life processes, such as genetic mutations and environmental changes, can lead to both evolutionary advancements and catastrophic events. This unpredictability is a fundamental aspect of life that makes it both fascinating and challenging to understand.

Data from various scientific studies support the book's claims. For instance, a study published in the journal "Nature" found that genetic mutations are a significant source of variation in populations, which is crucial for evolutionary processes (Hartl & Clark, 2007). Additionally, the Intergovernmental Panel on Climate Change (IPCC) has reported that climate change is causing unpredictable shifts in ecosystems, which can have severe consequences for biodiversity (IPCC, 2014). These examples illustrate the ongoing struggle for existence and the inherent unpredictability of life processes.

In conclusion, the core issue with life, as discussed in "What's the Matter with Life?", is the struggle for existence and the inherent unpredictability of life processes. This struggle is evident in the constant competition for resources and the evolutionary pressures that shape species. The inherent unpredictability arises from the chaotic nature of life processes, which can lead to both beneficial and detrimental outcomes. Scientific data from various studies further support these claims, highlighting the importance of understanding the complex dynamics of life.