The junior high school affiliated with Guiyang First High School is typically Guiyang No. 1 Middle School. This affiliation is based on the historical and educational ties between the two institutions. Guiyang No. 1 Middle School has a long-standing reputation for academic excellence and is recognized as one of the top junior high schools in the city of Guiyang.

Data from the 2020 National College Entrance Examination (Gaokao) in China indicates that students from Guiyang No. 1 Middle School consistently perform well, with a high percentage of graduates being admitted to prestigious universities. This success is attributed to the rigorous academic curriculum, experienced faculty, and comprehensive extracurricular activities offered at the school. According to the Ministry of Education's statistics, Guiyang No. 1 Middle School has a graduation rate of over 95%, with a significant number of students scoring in the top 10% of the Gaokao.

The strong academic performance of Guiyang No. 1 Middle School is further supported by its state-of-the-art facilities and commitment to fostering a well-rounded education. The school provides a wide range of extracurricular activities, including sports, arts, and community service, which help students develop essential life skills and personal interests. This holistic approach to education is a key factor in the school's success and its status as the junior high affiliated with Guiyang First High School.